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Journal articles

Glucose metabolic profiles evaluated by PET associated with molecular characteristic landscape of gastric cancer.

Although FDG-PET is widely used in cancer, its role in gastric cancer (GC) is still controversial due to variable [18F]fluorodeoxyglucose ([18F]FDG) uptake. Here, we sought to develop a genetic signat

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Journal articles

Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients

The Coronavirus disease 2019 (COVID-19) has been spreading worldwide with rapidly increased number of deaths.

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Journal articles

Discovery of molecular features underlying the morphological landscape by integrating spatial transcriptomic data with deep features of tissue images

Profiling molecular features associated with the morphological landscape of tissue is crucial for investigating the structural and spatial patterns that underlie the biological function of tissues. In

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Journal articles

Differences in Tumor Immune Microenvironment in Metastatic Sites of Breast Cancer

Tumor immune microenvironment (TIME) promotes immune escape, allowing for tumor progression and metastasis.

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Journal articles

Translating amyloid PET of different radiotracers by a deep generative model for interchangeability

It is challenging to compare amyloid PET images obtained with different radiotracers. Here, we introduce a new approach to improve the interchangeability of amyloid PET acquired with different radiotr

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Journal articles

Variability of FP-CIT PET Patterns Associated With Clinical Features of Multiple System Atrophy

To validate the role of the dopamine transporter (DAT) imaging as a biomarker in multiple system atrophy (MSA), we analyzed the association between spatial patterns of [18F]fluoro-propyl-carbomethoxy-

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Journal articles

Europium-Diethylenetriaminepentaacetic Acid Loaded Radioluminescence Liposome Nanoplatform for Effective Radioisotope-Mediated Photodynamic Therapy.

Photodynamic therapy (PDT) is an effective anticancer strategy with a higher selectivity and fewer adverse effects than conventional therapies; however, shallow tissue penetration depth of light has h

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Journal articles

Visual interpretation of [18F]Florbetaben PET supported by deep learning-based estimation of amyloid burden.

Amyloid PET which has been widely used for noninvasive assessment of cortical amyloid burden is visually interpreted in the clinical setting. As a fast and easy-to-use visual interpretation support sy

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Journal articles

Radiosensitizing high-Z metal nanoparticles for enhanced radiotherapy of glioblastoma multiforme.

Radiotherapy is an essential step during the treatment of glioblastoma multiforme (GBM), one of the most lethal malignancies. The survival in patients with GBM was improved by the current standard of

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