Portrai Insights
Insights on data analysis, AI, and the platform we're building at Portrai.
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63 articles
Comprehensive PortrAIgent Visium Analysis
This six-part series demonstrates an end-to-end spatial transcriptomics workflow using the PortrAIgent platform to analyze TNBC and ER+ breast cancer tissues by integrating Visium data with a…
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[Sid’s Data Journey - Part 3] Virtual Tissue Pharmacology: Bringing In Silico Drug Testing to a Patient Tissue
From target expression to tissue pharmacology: modeling how radiopharmaceuticals distribute, accumulate, and deliver dose across Sid’s tumor tissue.
[Sid’s Data Journey - Part 2] Beyond Expression: How to Evaluate Drug Targets
Why target expression alone is not enough. We compare coverage, heterogeneity, spatial distribution, and normal-tissue risk in Sid’s tumor.
[Sid’s Data Journey - Part 1] Single-Patient PortraiTARGET: Data-Driven Target Discovery for Personalized Drug Development
How one patient’s longitudinal single-cell and spatial data can be used to identify and prioritize therapeutic targets with PortraiTARGET.
Same Stage, Different Fates: Beyond TNM Staging, What Spatial Biology Reveals About Cancer
Where Does the Uncertainty for Patients and Physicians Come From? For physicians treating cancer in clinical practice, the most difficult moment is not necessarily when surgery technically fails.
Engineering and evaluation of precision-glycosylated clickable albumin nanoplatform for targeting the tumor microenvironment
Glycosylation of drug delivery vehicles enables selective tumor microenvironment (TME) targeting but is…
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Generating Single Cells with Language Models
Portrai VGL- Core AI of World Model From Cell-as-Text to In Silico Spatial Biology Spatial biology and single cell omics have reached an interesting point.
Generation of Super-resolution Images from Barcode-based Spatial Transcriptomics Using Deep Image Prior
Spatial transcriptomics (ST) has revolutionized the field of biology by providing a powerful tool for analyzing gene expression in situ.
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Spatial transcriptomics unveils landscape of resistance to concurrent chemo-radiotherapy in hypopharyngeal squamous cell carcinoma: the role of SPP1+ macrophages
Hypopharyngeal squamous cell carcinoma (SCC) is a highly aggressive cancer with a poor prognosis, particularly in advanced stages where…
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Portrai's Authors
Capturing and compounding Portrai's insights.
Daeseung Lee
CEO
Physician-scientist who left clinical practice to bring spatial biology into oncology drug discovery
Hongyoon Choi
CTO
Builds the algorithms that turn spatial transcriptomics into actionable target intelligence
Hyung-Jun Im
CSO
Nuclear medicine specialist linking imaging biomarkers to next-generation radiopharmaceuticals
Kwonjoong Na
CMO
Translates platform insights into IND-enabling decisions across oncology programs
Portrai
Official posts from the Portrai team, decoding disease with spatial intelligence