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Alzheimer’s Disease Neuroimaging Initiative. Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease
J Neuroinflammation. 2021 Aug 31;18(1):190. Abstract Background: Dynamically altered microglia play an important role in the progression of Alzheimer’s disease (AD). Here, we found a close associatio…
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Integrative analysis of FDG PET and transcriptome data for association of metabolic heterogeneity and tumor microenvironment of stomach cancer.
Journal of Nuclear Medicine, 61 (supplement 1) 1199. Abstract Introduction: The close interaction between cancer and immune cells in the tumor microenvironment (TME) affects the glucose metabolic pro…
Single-cell analysis reveals the key role of enhanced endothelial glucose uptake in neurometabolic coupling
Journal of Nuclear Medicine, 61 (supplement 1) 85. Abstract Objectives: Increased glucose uptake in the activated region of the brain known as neurometabolic coupling has long been widely accepted in…
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Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients
Scientific reports, 11(1), 1–9. Abstract The Coronavirus disease 2019 (COVID-19) has been spreading worldwide with rapidly increased number of deaths. Hyperinflammation mediated by dysregulated monoc…
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Integrative analysis of imaging and transcriptomic data of the immune landscape associated with tumor metabolism in lung adenocarcinoma: clinical and prognostic implications.
Theranostics, 8(7), 1956. Abstract Although metabolic modulation in the tumor microenvironment (TME) is one of the key mechanisms of cancer immune escape, there is a lack of understanding of the comp…
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