Portrai Insights
Insights on data analysis, AI, and the platform we're building at Portrai.
Showing articles by Portrai
Show all articlesLatest
55 articles
Comprehensive gene expression analysis for exploring the association between glucose metabolism and differentiation of thyroid cancer
BMC Cancer. 2019;19(1):1260. Abstract Background: The principle of loss of iodine uptake and increased glucose metabolism according to dedifferentiation of thyroid cancer is clinically assessed by im…
Portrai-
A pan-cancer analysis of the clinical and genetic portraits of somatostatin receptor expressing tumor as a potential target of peptide receptor imaging and therapy
EJNMMI Res. 2020;10(1):42. Abstract Purpose: Although somatostatin receptor (SST) is a promising theranostic target and is widely expressed in tumors of various organs, the indication for therapies t…
Portrai-
Tumor immune profiles noninvasively estimated by FDG PET with deep learning correlate with immunotherapy response in lung adenocarcinoma
Theranostics. 2020;10(23):10838–10848. Abstract The metabolic properties of tumor microenvironment (TME) are dynamically dysregulated to achieve immune escape and promote cancer cell survival. Howeve…
Portrai-
Differences in Tumor Immune Microenvironment in Metastatic Sites of Breast Cancer
Front Oncol. 2021;11:649004. Abstract Introduction: Tumor immune microenvironment (TIME) promotes immune escape, allowing for tumor progression and metastasis. In spite of the current evidence of the…
Portrai-
Glucose metabolic profiles evaluated by PET associated with molecular characteristic landscape of gastric cancer.
Gastric Cancer. 2021 Aug 7. doi: 10.1007/s10120–021–01223–3. Online ahead of print. Abstract Background: Although FDG-PET is widely used in cancer, its role in gastric cancer (GC) is still controvers…
Portrai-
Alzheimer’s Disease Neuroimaging Initiative. Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease
J Neuroinflammation. 2021 Aug 31;18(1):190. Background: Dynamically altered microglia play an important role in the progression of Alzheimer’s disease (AD). Here, we found a close association of the …
Portrai-
Single-cell analysis reveals the key role of enhanced endothelial glucose uptake in neurometabolic coupling
Journal of Nuclear Medicine, 61 (supplement 1) 85. Abstract Objectives: Increased glucose uptake in the activated region of the brain known as neurometabolic coupling has long been widely accepted in…
Portrai-
Discovery of molecular features underlying the morphological landscape by integrating spatial transcriptomic data with deep features of tissue images
Nucleic acids research, 49(10), e55-e55. Abstract Profiling molecular features associated with the morphological landscape of tissue is crucial for investigating the structural and spatial patterns t…
Portrai-
Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients
Scientific reports, 11(1), 1–9. Abstract The Coronavirus disease 2019 (COVID-19) has been spreading worldwide with rapidly increased number of deaths. Hyperinflammation mediated by dysregulated monoc…
Portrai-WRITTEN BY
Portrai's Authors
Capturing and compounding Portrai's insights.
Daeseung Lee
CEO
Physician-scientist who left clinical practice to bring spatial biology into oncology drug discovery
Hongyoon Choi
CTO
Builds the algorithms that turn spatial transcriptomics into actionable target intelligence
Hyung-Jun Im
CSO
Nuclear medicine specialist linking imaging biomarkers to next-generation radiopharmaceuticals
Kwonjoong Na
CMO
Translates platform insights into IND-enabling decisions across oncology programs
Portrai
Official posts from the Portrai team, decoding disease with spatial intelligence