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Portrai Insights

Insights on data analysis, AI, and the platform we're building at Portrai.

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56 articles
Journal articles

Engineering and evaluation of precision-glycosylated clickable albumin nanoplatform for targeting the tumor microenvironment

Glycosylation of drug delivery vehicles enables selective tumor microenvironment (TME) targeting but is…

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Journal articles

Generation of Super-resolution Images from Barcode-based Spatial Transcriptomics Using Deep Image Prior

Spatial transcriptomics (ST) has revolutionized the field of biology by providing a powerful tool for analyzing gene expression in situ.

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Journal articles

Spatial transcriptomics unveils landscape of resistance to concurrent chemo-radiotherapy in hypopharyngeal squamous cell carcinoma: the role of SPP1+ macrophages

Hypopharyngeal squamous cell carcinoma (SCC) is a highly aggressive cancer with a poor prognosis, particularly in advanced stages where…

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Journal articles

Analysis of Unmapped RNA-seq Data from Cancer Spatial Transcriptome to Decipher Cancer Microbiome

Recent research increasingly emphasizes the importance of the microbiome in the development and progression of cancer.

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Journal articles

Spatial Transcriptomics Reveals Spatially Diverse Cancer-Associated Fibroblast in Lung Squamous Cell Carcinoma Linked to Tumor Progression

While cancer-associated fibroblasts (CAFs) are crucial in influencing tumor growth and immune responses in lung cancer, we still lack a…

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Journal articles

CELLama: Foundation Model for Single Cell and Spatial Transcriptomics by Cell Embedding Leveraging Language Model Abilities

Large-scale single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) have transformed biomedical research into a data-driven…

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Journal articles

Prediction of post-stroke cognitive impairment using brain FDG PET: deep learning-based approach

Post-stroke cognitive impairment can affect up to one third of stroke survivors.

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Journal articles

Fully automated identification of brain abnormality from whole-body FDG-PET imaging using deep learning-based brain extraction and statistical parametric mapping

The whole brain is often covered in [18F]Fluorodeoxyglucose positron emission tomography ([18F]FDG-PET) in oncology patients, but the covered…

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Journal articles

Different Glucose Metabolic Features According to Cancer and Immune Cells in the Tumor Microenvironment

A close metabolic interaction between cancer and immune cells in the tumor microenvironment (TME) plays a pivotal role in cancer immunity.

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