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91 articles
Glucose metabolic profiles evaluated by PET associated with molecular characteristic landscape of gastric cancer
Although FDG-PET is widely used in cancer, its role in gastric cancer (GC) is still controversial due to variable [18F]fluorodeoxyglucose ([18F]FDG) uptake. Here, we sought to develop a genetic signat
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Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients
The Coronavirus disease 2019 (COVID-19) has been spreading worldwide with rapidly increased number of deaths.
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Discovery of molecular features underlying the morphological landscape by integrating spatial transcriptomic data with deep features of tissue images
Profiling molecular features associated with the morphological landscape of tissue is crucial for investigating the structural and spatial patterns that underlie the biological function of tissues. In
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Differences in Tumor Immune Microenvironment in Metastatic Sites of Breast Cancer
Tumor immune microenvironment (TIME) promotes immune escape, allowing for tumor progression and metastasis.
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Translating amyloid PET of different radiotracers by a deep generative model for interchangeability
It is challenging to compare amyloid PET images obtained with different radiotracers. Here, we introduce a new approach to improve the interchangeability of amyloid PET acquired with different radiotr
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Variability of FP-CIT PET Patterns Associated With Clinical Features of Multiple System Atrophy
To validate the role of the dopamine transporter (DAT) imaging as a biomarker in multiple system atrophy (MSA), we analyzed the association between spatial patterns of [18F]fluoro-propyl-carbomethoxy-
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Europium-Diethylenetriaminepentaacetic Acid Loaded Radioluminescence Liposome Nanoplatform for Effective Radioisotope-Mediated Photodynamic Therapy
Photodynamic therapy (PDT) is an effective anticancer strategy with a higher selectivity and fewer adverse effects than conventional therapies; however, shallow tissue penetration depth of light has h
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Visual interpretation of [18F]Florbetaben PET supported by deep learning-based estimation of amyloid burden
Amyloid PET which has been widely used for noninvasive assessment of cortical amyloid burden is visually interpreted in the clinical setting. As a fast and easy-to-use visual interpretation support sy
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Radiosensitizing high-Z metal nanoparticles for enhanced radiotherapy of glioblastoma multiforme
Radiotherapy is an essential step during the treatment of glioblastoma multiforme (GBM), one of the most lethal malignancies. The survival in patients with GBM was improved by the current standard of
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Portrai's Authors
Capturing and compounding Portrai's insights.
Daeseung Lee
CEO
Physician-scientist who left clinical practice to bring spatial biology into oncology drug discovery
Hongyoon Choi
CTO
Builds the algorithms that turn spatial transcriptomics into actionable target intelligence
Hyung-Jun Im
CSO
Nuclear medicine specialist linking imaging biomarkers to next-generation radiopharmaceuticals
Kwonjoong Na
CMO
Translates platform insights into IND-enabling decisions across oncology programs
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Official posts from the Portrai team, decoding disease with spatial intelligence