Portrai Insights
Insights on data analysis, AI, and the platform we're building at Portrai.
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56 articles
Comprehensive gene expression analysis for exploring the association between glucose metabolism and differentiation of thyroid cancer
BMC Cancer. 2019;19(1):1260. Abstract Background: The principle of loss of iodine uptake and increased glucose metabolism according to dedifferentiation of thyroid cancer is clinically assessed by im…
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A pan-cancer analysis of the clinical and genetic portraits of somatostatin receptor expressing tumor as a potential target of peptide receptor imaging and therapy
EJNMMI Res. 2020;10(1):42. Abstract Purpose: Although somatostatin receptor (SST) is a promising theranostic target and is widely expressed in tumors of various organs, the indication for therapies t…
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Tumor immune profiles noninvasively estimated by FDG PET with deep learning correlate with immunotherapy response in lung adenocarcinoma
Theranostics. 2020;10(23):10838–10848. Abstract The metabolic properties of tumor microenvironment (TME) are dynamically dysregulated to achieve immune escape and promote cancer cell survival. Howeve…
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Differences in Tumor Immune Microenvironment in Metastatic Sites of Breast Cancer
Front Oncol. 2021;11:649004. Abstract Introduction: Tumor immune microenvironment (TIME) promotes immune escape, allowing for tumor progression and metastasis. In spite of the current evidence of the…
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Glucose metabolic profiles evaluated by PET associated with molecular characteristic landscape of gastric cancer.
Gastric Cancer. 2021 Aug 7. doi: 10.1007/s10120–021–01223–3. Online ahead of print. Abstract Background: Although FDG-PET is widely used in cancer, its role in gastric cancer (GC) is still controvers…
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Alzheimer’s Disease Neuroimaging Initiative. Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease
J Neuroinflammation. 2021 Aug 31;18(1):190. Background: Dynamically altered microglia play an important role in the progression of Alzheimer’s disease (AD). Here, we found a close association of the …
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Integrative analysis of FDG PET and transcriptome data for association of metabolic heterogeneity and tumor microenvironment of stomach cancer.
Journal of Nuclear Medicine, 61 (supplement 1) 1199. Abstract Introduction: The close interaction between cancer and immune cells in the tumor microenvironment (TME) affects the glucose metabolic pro…
Single-cell analysis reveals the key role of enhanced endothelial glucose uptake in neurometabolic coupling
Journal of Nuclear Medicine, 61 (supplement 1) 85. Abstract Objectives: Increased glucose uptake in the activated region of the brain known as neurometabolic coupling has long been widely accepted in…
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Discovery of molecular features underlying the morphological landscape by integrating spatial transcriptomic data with deep features of tissue images
Nucleic acids research, 49(10), e55-e55. Abstract Profiling molecular features associated with the morphological landscape of tissue is crucial for investigating the structural and spatial patterns t…
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Portrai's Authors
Capturing and compounding Portrai's insights.
Daeseung Lee
CEO
Physician-scientist who left clinical practice to bring spatial biology into oncology drug discovery
Hongyoon Choi
CTO
Builds the algorithms that turn spatial transcriptomics into actionable target intelligence
Hyung-Jun Im
CSO
Nuclear medicine specialist linking imaging biomarkers to next-generation radiopharmaceuticals
Kwonjoong Na
CMO
Translates platform insights into IND-enabling decisions across oncology programs
Portrai
Official posts from the Portrai team, decoding disease with spatial intelligence