Portrai Insights
Insights on data analysis, AI, and the platform we're building at Portrai.
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Peptide-based theranostics targeting ANTXR1 in cancer stroma Available
ANTXR1 is one of the pancreatic ductal adenocarcinoma (PDAC) stroma-specific cell surface markers (Ref 1), which is also overexpressed in the stroma of various cancer types. Radiotheranostics refers..
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Mapping cell types in the tumor microenvironment from tissue images via deep learning trained by spatial transcriptomics of lung adenocarcinoma
Profiling heterogeneous cell types in the tumor microenvironment (TME) is important for cancer immunotherapy.
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GeneDART: Extending gene coverage in image-based spatial transcriptomics by deep learning-based domain adaptation with barcode-based RNA-sequencing data
Spatial transcriptomics (ST) technologies provide comprehensive biological insights regarding cell-cell interactions and peri-cellular…
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STopover captures spatial colocalization and interaction in the tumor microenvironment using topological analysis in spatial transcriptomics data
Unraveling the spatial configuration of the tumor microenvironment (TME) is key to understanding tumor-immune interactions to translate them…
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Discovery of stromal targets in pancreatic cancer Available
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies with limited treatment options. Development of stroma targeting therapeutics for PDAC is gaining attention because…
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Deep learning-based tumor microenvironment cell types mapping from H&E images of lung adenocarcinoma using spatial transcriptomic data
Spatial characterization of cell types of the tumor microenvironment (TME) is a key to finding new targets as well as developing biomarkers for immuno-oncology treatment.
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Spatial Transcriptomics-based Identification of Molecular Markers for Nanomedicine Distribution in Tumor Tissue
The intratumoral accumulation of nanomedicine has been considered a passive process, referred to as the enhanced permeability and retention…
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CellDART: cell type inference by domain adaptation of single-cell and spatial transcriptomic data
Deciphering the cellular composition in genome-wide spatially resolved transcriptomic data is a critical task to clarify the spatial context of cells in a…
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Alzheimer’s Disease Neuroimaging Initiative. Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease
Dynamically altered microglia play an important role in the progression of Alzheimer’s disease (AD).
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Portrai's Authors
Capturing and compounding Portrai's insights.
Daeseung Lee
CEO
Physician-scientist who left clinical practice to bring spatial biology into oncology drug discovery
Hongyoon Choi
CTO
Builds the algorithms that turn spatial transcriptomics into actionable target intelligence
Hyung-Jun Im
CSO
Nuclear medicine specialist linking imaging biomarkers to next-generation radiopharmaceuticals
Kwonjoong Na
CMO
Translates platform insights into IND-enabling decisions across oncology programs
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Official posts from the Portrai team, decoding disease with spatial intelligence