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Prediction of post-stroke cognitive impairment using brain FDG PET: deep learning-based approach
Eur J Nucl Med Mol Imaging. 2021 Oct 2. Epub ahead of print. PMID: 34599654. Abstract Purpose: Post-stroke cognitive impairment can affect up to one third of stroke survivors. Since cognitive functio…
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Fully automated identification of brain abnormality from whole-body FDG-PET imaging using deep learning-based brain extraction and statistical parametric mapping
EJNMMI Phys. 2021 Nov 14;8(1):79. Abstract Background: The whole brain is often covered in [18F]Fluorodeoxyglucose positron emission tomography ([18F]FDG-PET) in oncology patients, but the covered br…
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Different Glucose Metabolic Features According to Cancer and Immune Cells in the Tumor Microenvironment
Front. Oncol. 11:769393 Abstract Background: A close metabolic interaction between cancer and immune cells in the tumor microenvironment (TME) plays a pivotal role in cancer immunity. Herein, we have…
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Re-assessing the enhanced permeability and retention effect in peripheral arterial disease using radiolabeled long circulating nanoparticles
Biomaterials. 2016 Sep;100:101–9. Abstract As peripheral arterial disease (PAD) results in muscle ischemia and neovascularization, it has been claimed that nanoparticles can passively accumulate in i…
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Accelerated Blood Clearance Phenomenon Reduces the Passive Targeting of PEGylated Nanoparticles in Peripheral Arterial Disease.
ACS Appl Mater Interfaces. 2016 Jul 20;8(28):17955–63. Abstract Peripheral arterial disease (PAD) is a leading global health concern. Due to limited imaging and therapeutic options, PAD and other isc…
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Noninvasive Imaging of Myocardial Inflammation in Myocarditis using 68Ga-tagged Mannosylated Human Serum Albumin Positron Emission Tomography.
Theranostics. 2017 Jan 1;7(2):413–424. Abstract The diagnosis of myocarditis traditionally relies on invasive endomyocardial biopsy but none of the imaging studies so far are specific for infiltratio…
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Radiolabeled pertuzumab for imaging of human epidermal growth factor receptor 2 expression in ovarian cancer
Eur J Nucl Med Mol Imaging. 2017 Aug;44(8):1296–1305. Abstract Purpose: Human epidermal growth factor receptor 2 (HER2) is over-expressed in over 30% of ovarian cancer cases, playing an essential rol…
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DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury
Nat Biomed Eng. 2018 Nov;2(11):865–877. Abstract Patients with acute kidney injury (AKI) frequently require kidney transplantation and supportive therapies, such as rehydration and dialysis. Here, we…
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Development of 99mTc-Labeled Human Serum Albumin with Prolonged Circulation by Chelate-then-Click Approach: A Potential Blood Pool Imaging Agent.
Mol Pharm. 2019 Apr 1;16(4):1586–1595. Abstract Technetium-99m-labeled human serum albumin (99mTc-HSA) has been utilized as a blood pool imaging agent in the clinic for several decades. However, 99mT…
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