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55 articles
Accelerated Blood Clearance Phenomenon Reduces the Passive Targeting of PEGylated Nanoparticles in Peripheral Arterial Disease
ACS Appl Mater Interfaces. 2016 Jul 20;8(28):17955–63. Abstract Peripheral arterial disease (PAD) is a leading global health concern. Due to limited imaging and therapeutic options, PAD and other isc…
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Noninvasive Imaging of Myocardial Inflammation in Myocarditis using 68Ga-tagged Mannosylated Human Serum Albumin Positron Emission Tomography
Theranostics. 2017 Jan 1;7(2):413–424. Abstract The diagnosis of myocarditis traditionally relies on invasive endomyocardial biopsy but none of the imaging studies so far are specific for infiltratio…
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Radiolabeled pertuzumab for imaging of human epidermal growth factor receptor 2 expression in ovarian cancer
Eur J Nucl Med Mol Imaging. 2017 Aug;44(8):1296–1305. Abstract Purpose: Human epidermal growth factor receptor 2 (HER2) is over-expressed in over 30% of ovarian cancer cases, playing an essential rol…
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DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury
Nat Biomed Eng. 2018 Nov;2(11):865–877. Abstract Patients with acute kidney injury (AKI) frequently require kidney transplantation and supportive therapies, such as rehydration and dialysis. Here, we…
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Development of 99mTc-Labeled Human Serum Albumin with Prolonged Circulation by Chelate-then-Click Approach: A Potential Blood Pool Imaging Agent
Mol Pharm. 2019 Apr 1;16(4):1586–1595. Abstract Technetium-99m-labeled human serum albumin (99mTc-HSA) has been utilized as a blood pool imaging agent in the clinic for several decades. However, 99mT…
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Versatile and Finely Tuned Albumin Nanoplatform based on Click Chemistry
Theranostics. 2019 May 18;9(12):3398–3409. Abstract Albumin is one of the most attractive nanoplatforms for targeted imaging and drug delivery due to its biocompatibility and long circulation half-li…
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Theranostics Based on Liposome: Looking Back and Forward
Nucl Med Mol Imaging. 2019 Aug;53(4):242–246. Abstract Liposome is one of the oldest yet most successful nanomedicine platforms. Doxil®, PEGylated liposome loaded with doxorubicin (DOX), was approved…
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Efficient renal clearance of DNA tetrahedron nanoparticles enables quantitative evaluation of kidney function.
Nano Res. 2019 Mar;12(3):637–642. Abstract DNA tetrahedron nanostructure (DTN) is one of the simplest DNA nanostructures and has been successfully applied for biosensing, imaging, and treatment of ca…
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Europium-Diethylenetriaminepentaacetic Acid Loaded Radioluminescence Liposome Nanoplatform for Effective Radioisotope-Mediated Photodynamic Therapy
ACS Nano. 2020 Oct 27;14(10):13004–13015. Abstract Photodynamic therapy (PDT) is an effective anticancer strategy with a higher selectivity and fewer adverse effects than conventional therapies; howe…
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Portrai's Authors
Capturing and compounding Portrai's insights.
Daeseung Lee
CEO
Physician-scientist who left clinical practice to bring spatial biology into oncology drug discovery
Hongyoon Choi
CTO
Builds the algorithms that turn spatial transcriptomics into actionable target intelligence
Hyung-Jun Im
CSO
Nuclear medicine specialist linking imaging biomarkers to next-generation radiopharmaceuticals
Kwonjoong Na
CMO
Translates platform insights into IND-enabling decisions across oncology programs
Portrai
Official posts from the Portrai team, decoding disease with spatial intelligence