Portrai Insights
Insights on data analysis, AI, and the platform we're building at Portrai.
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27 articles
A Sneeze Shouldn't Ruin an AI Model: Why Portrai is Automating Visium HD with ABLE Labs
Spatial Transcriptomics (ST) is changing the landscape of precision oncology by decoding both the location and gene expression of cells simultaneously. Yet, behind the stunning AI-generated maps...
Integrating Spatial Transcriptomics and Drug Imaging: A New Paradigm for Evaluating Precision Drug Delivery Systems
Portrai’s Next Step in Precision DDS When designing precision drug delivery systems (DDS), the key question is no longer simply, “Does the drug reach the tumor?”
20 µm Distance and 150 µm Boundary: When Spatial Metrics Split Treatment Response
Returning to “Same Stage, Different Destiny” In my previous post, I wrote that TNM staging is an excellent method of assessment, but it cannot fully describe the blueprint of a tumor—namely, the…
Spatial Biology as a Patient-Centric Data OS for the AI Era
The Rise of Spatial Biology A Shift in How We View Biology Our approach to investigating biological phenomena and understanding disease has long begun with identifying changes at the cellular and…
Next-Generation AI in Biology & Medicine in the Age of AI
0. The Rise of Spatial Biology Our efforts to explore biological phenomena and understand disease have long focused on changes occurring at the cellular and molecular levels.
Same Stage, Different Fates: Beyond TNM Staging, What Spatial Biology Reveals About Cancer
Where Does the Uncertainty for Patients and Physicians Come From? For physicians treating cancer in clinical practice, the most difficult moment is not necessarily when surgery technically fails.
Generating Single Cells with Language Models
Portrai VGL- Core AI of World Model From Cell-as-Text to In Silico Spatial Biology Spatial biology and single cell omics have reached an interesting point.
Comparative analysis and integration of image-based and high-resolution sequence-based spatial transcriptomics platforms for tumor microenvironment analysis
Advances in spatial transcriptomics (ST) enable precise gene expression analysis within the tumor microenvironment (TME). VisiumHD and Xenium Prime 5K are cutting-edge platforms offering unique str...
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Target-based Understanding the Termination of the AMG 794 Clinical Trial: A Deep Dive with spatial transcriptomics data
Amgen has exited the competitive development of Claudin 6 (CLDN6) therapies, which is still in its early stages, based on initial data from preclinical studies. Amgen, on July 5th 2024, had terminated
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Portrai's Authors
Capturing and compounding Portrai's insights.
Daeseung Lee
CEO
Physician-scientist who left clinical practice to bring spatial biology into oncology drug discovery
Hongyoon Choi
CTO
Builds the algorithms that turn spatial transcriptomics into actionable target intelligence
Hyung-Jun Im
CSO
Nuclear medicine specialist linking imaging biomarkers to next-generation radiopharmaceuticals
Kwonjoong Na
CMO
Translates platform insights into IND-enabling decisions across oncology programs
Portrai
Official posts from the Portrai team, decoding disease with spatial intelligence